The town of Berlin Maryland had its start around the 1790s, part of the Burley Plantation, a 300-acre land grant dating back to 1677. The name Berlin is believed to be derived from a contraction of "Burleigh Inn", a tavern located at the crossroads of the Philadelphia Post Road (now South Main Street) and Sinepuxent Road (Tripoli Street).
   Berlin Maryland incorporated as a town in 1868. In the early 21st century, Berlin was known as a rest stop for travelers on their way to the coastal resort of Ocean City MD as well as a stop for tourists who enjoyed hunting and fishing on the lower Eastern Shore of Maryland.